Funded Projects

The core infrastructure of the Microbiota Therapeutics Outcomes Program is supported by a University of Toronto Department of Medicine Integrating Challenge Grant.

There are three funded studies currently involved with the MTOP.

1. Long-term Measurement of Multidisciplinary Outcomes in Patients Receiving Fecal Microbiota Transplantation (FMT) in the University of Toronto Microbiota Therapeutics Outcomes Program (MTOP)

Principal Investigators: Susy Hota, Susan M. Poutanen

Funding Agency:  Department of Medicine Integrating Challenge Grant Program

             Contact person: Jenita Chrysostoum, jenita.chrysostoum@uhn.ca  / 416-340-4800                                               ext. 8353

2. Fecal microbiota transplant from healthy lean donors to morbidly obese individuals: effect on insulin resistance and other obesity-related parameters. A randomized controlled trial.

 Principal Investigator: Dr. Johane Allard

 Funding Agency: CIHR

            Description: Our hypothesis is that a fecal transplant from healthy lean donors into morbidly obese subjects will lead to an improvement in glucose metabolism and to a reduction in body weight, appetite, and food intake as well as to an improvement in quality of life, depression and anxiety scores. This is an ongoing study and recruitment is still active.

 Contact person: Monica Laura Ponta,  monica.ponta@uhnresearch.ca / 416-340-4413

 3. Name of the Study: A Randomized Controlled Trial of the Safety and Efficacy of Fecal Microbiota Transplantation in a Population with Bipolar Disorder

Principal investigator: Dr. Valerie Taylor

Funding Agency: The Stanley Medical Research Institute (SMRI)

Contact person: Asem Bala, asem.bala@wchospital.ca / 416-351-3732 ext. 2301

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